8R-1195
TL;DR: 8R-1195 (CAS 478260-50-3) is a chemical compound with molecular formula C26H28FN3OS and molecular weight 449.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2,4-dimethylphenyl)sulfanyl-N-[3-fluoro-4-(4-phenylpiperazin-1-yl)phenyl]acetamide
Also Known As: 8R-1195, 2-(2,4-dimethylphenyl)sulfanyl-N-[3-fluoro-4-(4-phenylpiperazin-1-yl)phenyl]acetamide, 2-[(2,4-dimethylphenyl)sulfanyl]-N-[3-fluoro-4-(4-phenylpiperazino)phenyl]acetamide, 2-[(2,4-dimethylphenyl)sulfanyl]-N-[3-fluoro-4-(4-phenylpiperazin-1-yl)phenyl]acetamide
| Molecular Formula | C26H28FN3OS |
|---|---|
| Molecular Weight | 449.19 g/mol |
| LogP | 5.49994 |
| Topological Polar Surface Area | 35.58 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 449.19373 |
| Heavy Atoms | 32 |
| Complexity | 1081.685 |
Chemical Identifiers
| CAS Number | 478260-50-3 |
|---|---|
| SMILES | CC1=CC(=C(C=C1)SCC(=O)NC2=CC(=C(C=C2)N3CCN(CC3)C4=CC=CC=C4)F)C |
Product Overview
8R-1195 (CAS 478260-50-3), with molecular formula C26H28FN3OS and molecular weight 449.19 g/mol. IUPAC: 2-(2,4-dimethylphenyl)sulfanyl-N-[3-fluoro-4-(4-phenylpiperazin-1-yl)phenyl]acetamide.
Chemical Property Profile of 8R-1195
Property Insights of 8R-1195
The XLogP value of 5.49994 indicates that 8R-1195 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.58 Ų, 8R-1195 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8R-1195 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8R-1195?
The CAS number of 8R-1195 is 478260-50-3.
What is the molecular formula of 8R-1195?
The molecular formula of 8R-1195 is C26H28FN3OS.
What is the molecular weight of 8R-1195?
The molecular weight of 8R-1195 is 449.19 g/mol.
Where can I buy 8R-1195?
You can request a quote for 8R-1195 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8R-1195?
Yes, KEHONG BIO provides custom synthesis services for 8R-1195 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.