1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone
TL;DR: 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone (CAS 478259-73-3) is a chemical compound with molecular formula C12H9F3N2OS and molecular weight 286.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-[4-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]ethanone
Also Known As: 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone, 1-(2-(4-(trifluoromethyl)phenylamino)thiazol-5-yl)ethanone, 1-{2-[4-(trifluoromethyl)anilino]-1,3-thiazol-5-yl}-1-ethanone, 1-(2-{[4-(trifluoromethyl)phenyl]amino}-1,3-thiazol-5-yl)ethan-1-one, 8R-0336
| Molecular Formula | C12H9F3N2OS |
|---|---|
| Molecular Weight | 286.04 g/mol |
| LogP | 4.1081 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 286.03876 |
| Heavy Atoms | 19 |
| Complexity | 589.7671 |
Chemical Identifiers
| CAS Number | 478259-73-3 |
|---|---|
| SMILES | CC(=O)C1=CN=C(S1)NC2=CC=C(C=C2)C(F)(F)F |
Product Overview
1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone (CAS 478259-73-3), with molecular formula C12H9F3N2OS and molecular weight 286.04 g/mol. IUPAC: 1-[2-[4-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]ethanone.
Chemical Property Profile of 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone
Property Insights of 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone
The XLogP value of 4.1081 indicates that 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone?
The CAS number of 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone is 478259-73-3.
What is the molecular formula of 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone?
The molecular formula of 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone is C12H9F3N2OS.
What is the molecular weight of 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone?
The molecular weight of 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone is 286.04 g/mol.
Where can I buy 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone?
You can request a quote for 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-((4-(Trifluoromethyl)phenyl)amino)thiazol-5-yl)ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.