8R-0269 structure

8R-0269

TL;DR: 8R-0269 (CAS 478259-46-0) is a chemical compound with molecular formula C19H15Cl2FN2O3 and molecular weight 408.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-(2-chloro-6-fluorophenyl)-N-[(3-chloro-4-methoxyphenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide

Also Known As: 8R-0269, 3-(2-chloro-6-fluorophenyl)-N-(3-chloro-4-methoxybenzyl)-5-methyl-4-isoxazolecarboxamide, 3-(2-chloro-6-fluorophenyl)-N-[(3-chloro-4-methoxyphenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide, N-[(3-chloro-4-methoxyphenyl)methyl]-3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamide

CAS: 478259-46-0
Molecular Formula C19H15Cl2FN2O3
Molecular Weight 408.04 g/mol
LogP 5.03452
Topological Polar Surface Area 64.36 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 5
Exact Mass 408.04437
Heavy Atoms 27
Complexity 984.365

Chemical Identifiers

CAS Number 478259-46-0
SMILES CC1=C(C(=NO1)C2=C(C=CC=C2Cl)F)C(=O)NCC3=CC(=C(C=C3)OC)Cl

Product Overview

8R-0269 (CAS 478259-46-0), with molecular formula C19H15Cl2FN2O3 and molecular weight 408.04 g/mol. IUPAC: 3-(2-chloro-6-fluorophenyl)-N-[(3-chloro-4-methoxyphenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 8R-0269

XLogP
5.03452
TPSA (Topological Polar Surface Area)
64.36
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
5
Heavy Atoms
27
Complexity
984.365
Exact Mass
408.04437
Monoisotopic Mass
408.04437
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8R-0269

The XLogP value of 5.03452 indicates that 8R-0269 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.36 Ų falls within the moderate polarity range, balancing permeability and solubility for 8R-0269. Following Lipinski's Rule of Five, 8R-0269 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8R-0269?

The CAS number of 8R-0269 is 478259-46-0.

What is the molecular formula of 8R-0269?

The molecular formula of 8R-0269 is C19H15Cl2FN2O3.

What is the molecular weight of 8R-0269?

The molecular weight of 8R-0269 is 408.04 g/mol.

Where can I buy 8R-0269?

You can request a quote for 8R-0269 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8R-0269?

Yes, KEHONG BIO provides custom synthesis services for 8R-0269 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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