2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone
TL;DR: 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone (CAS 478258-79-6) is a chemical compound with molecular formula C7H10ClF2NO2 and molecular weight 213.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-2,2-difluoro-1-(4-hydroxypiperidin-1-yl)ethanone
Also Known As: 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone, 4-Piperidinol,1- -, 2-chloro-2,2-difluoro-1-(4-hydroxypiperidin-1-yl)ethanone, chlorodifluorohydroxypiperidinoethanone, 4-Piperidinol, 1-(chlorodifluoroacetyl)- (9CI)
| Molecular Formula | C7H10ClF2NO2 |
|---|---|
| Molecular Weight | 213.04 g/mol |
| LogP | 0.8013 |
| Topological Polar Surface Area | 40.54 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 213.03682 |
| Heavy Atoms | 13 |
| Complexity | 199.15945 |
Chemical Identifiers
| CAS Number | 478258-79-6 |
|---|---|
| SMILES | C1CN(CCC1O)C(=O)C(F)(F)Cl |
Product Overview
2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone (CAS 478258-79-6), with molecular formula C7H10ClF2NO2 and molecular weight 213.04 g/mol. IUPAC: 2-chloro-2,2-difluoro-1-(4-hydroxypiperidin-1-yl)ethanone.
Chemical Property Profile of 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone
Property Insights of 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone
The XLogP value of 0.8013 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone. With a topological polar surface area (TPSA) of 40.54 Ų, 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone?
The CAS number of 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone is 478258-79-6.
What is the molecular formula of 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone?
The molecular formula of 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone is C7H10ClF2NO2.
What is the molecular weight of 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone?
The molecular weight of 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone is 213.04 g/mol.
Where can I buy 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone?
You can request a quote for 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-2,2-difluoro-1-(4-hydroxypiperidino)-1-ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.