N-benzyl-2-chloro-2,2-difluoroacetamide
TL;DR: N-benzyl-2-chloro-2,2-difluoroacetamide (CAS 478258-77-4) is a chemical compound with molecular formula C9H8ClF2NO and molecular weight 219.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-benzyl-2-chloro-2,2-difluoroacetamide
Also Known As: N-benzyl-2-chloro-2,2-difluoroacetamide, N-benzyl-2-chloro-2,2-difluoro-acetamide, 8P-923, 2-Chloro-2,2-difluoro-N-(phenylmethyl)acetamide
| Molecular Formula | C9H8ClF2NO |
|---|---|
| Molecular Weight | 219.03 g/mol |
| LogP | 2.1344 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 3 |
| Exact Mass | 219.02625 |
| Heavy Atoms | 14 |
| Complexity | 310.33804 |
Chemical Identifiers
| CAS Number | 478258-77-4 |
|---|---|
| SMILES | C1=CC=C(C=C1)CNC(=O)C(F)(F)Cl |
Product Overview
N-benzyl-2-chloro-2,2-difluoroacetamide (CAS 478258-77-4), with molecular formula C9H8ClF2NO and molecular weight 219.03 g/mol. IUPAC: N-benzyl-2-chloro-2,2-difluoroacetamide.
Chemical Property Profile of N-benzyl-2-chloro-2,2-difluoroacetamide
Property Insights of N-benzyl-2-chloro-2,2-difluoroacetamide
The XLogP value of 2.1344 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-benzyl-2-chloro-2,2-difluoroacetamide. With a topological polar surface area (TPSA) of 29.1 Ų, N-benzyl-2-chloro-2,2-difluoroacetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-benzyl-2-chloro-2,2-difluoroacetamide has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-benzyl-2-chloro-2,2-difluoroacetamide?
The CAS number of N-benzyl-2-chloro-2,2-difluoroacetamide is 478258-77-4.
What is the molecular formula of N-benzyl-2-chloro-2,2-difluoroacetamide?
The molecular formula of N-benzyl-2-chloro-2,2-difluoroacetamide is C9H8ClF2NO.
What is the molecular weight of N-benzyl-2-chloro-2,2-difluoroacetamide?
The molecular weight of N-benzyl-2-chloro-2,2-difluoroacetamide is 219.03 g/mol.
Where can I buy N-benzyl-2-chloro-2,2-difluoroacetamide?
You can request a quote for N-benzyl-2-chloro-2,2-difluoroacetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-benzyl-2-chloro-2,2-difluoroacetamide?
Yes, KEHONG BIO provides custom synthesis services for N-benzyl-2-chloro-2,2-difluoroacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.