Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate
TL;DR: Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate (CAS 478258-74-1) is a chemical compound with molecular formula C11H18F3NO3 and molecular weight 269.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate
Also Known As: Bionet2_000376, ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate, 8P-916, ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)-4-piperidinecarboxylate, 1-(3,3,3-TRIFLUORO-2-HYDROXY-PROPYL)-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
| Molecular Formula | C11H18F3NO3 |
|---|---|
| Molecular Weight | 269.12 g/mol |
| LogP | 1.1847 |
| Topological Polar Surface Area | 49.77 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 269.12387 |
| Heavy Atoms | 18 |
| Complexity | 275.19724 |
Chemical Identifiers
| CAS Number | 478258-74-1 |
|---|---|
| SMILES | CCOC(=O)C1CCN(CC1)CC(C(F)(F)F)O |
Product Overview
Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate (CAS 478258-74-1), with molecular formula C11H18F3NO3 and molecular weight 269.12 g/mol. IUPAC: ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate.
Chemical Property Profile of Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate
Property Insights of Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate
The XLogP value of 1.1847 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate. With a topological polar surface area (TPSA) of 49.77 Ų, Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate?
The CAS number of Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate is 478258-74-1.
What is the molecular formula of Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate?
The molecular formula of Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate is C11H18F3NO3.
What is the molecular weight of Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate?
The molecular weight of Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate is 269.12 g/mol.
Where can I buy Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate?
You can request a quote for Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for Ethyl 1-(3,3,3-trifluoro-2-hydroxypropyl)piperidine-4-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.