![1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole structure](/static/products/4782/478258-72-9.webp)
1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole
TL;DR: 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole (CAS 478258-72-9) is a chemical compound with molecular formula C12H9ClN2S and molecular weight 248.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-5-(indol-1-ylmethyl)-1,3-thiazole
Also Known As: 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole, 2-chloro-5-(indol-1-ylmethyl)-1,3-thiazole, 2-chloro-5-(indol-1-ylmethyl)thiazole, 8P-905, 1-[(2-chloro-1,3-thiazol-5-yl)methyl]indole
| Molecular Formula | C12H9ClN2S |
|---|---|
| Molecular Weight | 248.02 g/mol |
| LogP | 3.7995 |
| Topological Polar Surface Area | 17.82 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 248.0175 |
| Heavy Atoms | 16 |
| Complexity | 626.5301 |
Chemical Identifiers
| CAS Number | 478258-72-9 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C=CN2CC3=CN=C(S3)Cl |
Product Overview
1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole (CAS 478258-72-9), with molecular formula C12H9ClN2S and molecular weight 248.02 g/mol. IUPAC: 2-chloro-5-(indol-1-ylmethyl)-1,3-thiazole.
Chemical Property Profile of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole
Property Insights of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole
The XLogP value of 3.7995 indicates that 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.82 Ų, 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole?
The CAS number of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole is 478258-72-9.
What is the molecular formula of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole?
The molecular formula of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole is C12H9ClN2S.
What is the molecular weight of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole?
The molecular weight of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole is 248.02 g/mol.
Where can I buy 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole?
You can request a quote for 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole?
Yes, KEHONG BIO provides custom synthesis services for 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.