![8-[(2-Chloro-5-thiazolyl)methoxy]quinoline structure](/static/products/4782/478246-28-5.webp)
8-[(2-Chloro-5-thiazolyl)methoxy]quinoline
TL;DR: 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline (CAS 478246-28-5) is a chemical compound with molecular formula C13H9ClN2OS and molecular weight 276.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-5-(quinolin-8-yloxymethyl)-1,3-thiazole
Also Known As: 8-[(2-chloro-1,3-thiazol-5-yl)methoxy]quinoline, 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline, 2-chloro-5-(8-quinolyloxymethyl)thiazole, 2-chloro-5-(quinolin-8-yloxymethyl)-1,3-thiazole, 8-((2-Chloro-5-thiazolyl)methoxy)quinoline
| Molecular Formula | C13H9ClN2OS |
|---|---|
| Molecular Weight | 276.01 g/mol |
| LogP | 3.9237 |
| Topological Polar Surface Area | 35.01 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 276.01242 |
| Heavy Atoms | 18 |
| Complexity | 678.0678 |
Chemical Identifiers
| CAS Number | 478246-28-5 |
|---|---|
| SMILES | C1=CC2=C(C(=C1)OCC3=CN=C(S3)Cl)N=CC=C2 |
Product Overview
8-[(2-Chloro-5-thiazolyl)methoxy]quinoline (CAS 478246-28-5), with molecular formula C13H9ClN2OS and molecular weight 276.01 g/mol. IUPAC: 2-chloro-5-(quinolin-8-yloxymethyl)-1,3-thiazole.
Chemical Property Profile of 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline
Property Insights of 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline
The XLogP value of 3.9237 indicates that 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.01 Ų, 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline?
The CAS number of 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline is 478246-28-5.
What is the molecular formula of 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline?
The molecular formula of 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline is C13H9ClN2OS.
What is the molecular weight of 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline?
The molecular weight of 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline is 276.01 g/mol.
Where can I buy 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline?
You can request a quote for 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline?
Yes, KEHONG BIO provides custom synthesis services for 8-[(2-Chloro-5-thiazolyl)methoxy]quinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.