2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol
TL;DR: 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol (CAS 478079-32-2) is a chemical compound with molecular formula C11H10ClF2NO and molecular weight 245.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-2,2-difluoro-1-(1-methylindol-3-yl)ethanol
Also Known As: 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)ethan-1-ol, 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol, 2-chloro-2,2-difluoro-1-(1-methylindol-3-yl)ethanol, 7R-1073, I+/--(Chlorodifluoromethyl)-1-methyl-1H-indole-3-methanol
| Molecular Formula | C11H10ClF2NO |
|---|---|
| Molecular Weight | 245.04 g/mol |
| LogP | 3.0433 |
| Topological Polar Surface Area | 25.16 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 245.0419 |
| Heavy Atoms | 16 |
| Complexity | 518.1692 |
Chemical Identifiers
| CAS Number | 478079-32-2 |
|---|---|
| SMILES | CN1C=C(C2=CC=CC=C21)C(C(F)(F)Cl)O |
Product Overview
2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol (CAS 478079-32-2), with molecular formula C11H10ClF2NO and molecular weight 245.04 g/mol. IUPAC: 2-chloro-2,2-difluoro-1-(1-methylindol-3-yl)ethanol.
Chemical Property Profile of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol
Property Insights of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol
The XLogP value of 3.0433 indicates that 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 25.16 Ų, 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol?
The CAS number of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol is 478079-32-2.
What is the molecular formula of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol?
The molecular formula of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol is C11H10ClF2NO.
What is the molecular weight of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol?
The molecular weight of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol is 245.04 g/mol.
Where can I buy 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol?
You can request a quote for 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol?
Yes, KEHONG BIO provides custom synthesis services for 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.