2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone
TL;DR: 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone (CAS 478079-31-1) is a chemical compound with molecular formula C11H8ClF2NO and molecular weight 243.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-2,2-difluoro-1-(1-methylindol-3-yl)ethanone
Also Known As: 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone, 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)ethan-1-one, 2-chloro-2,2-difluoro-1-(1-methylindol-3-yl)ethanone, Ethanone, 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)- (9CI), 2-Chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)ethanone
| Molecular Formula | C11H8ClF2NO |
|---|---|
| Molecular Weight | 243.03 g/mol |
| LogP | 3.1926 |
| Topological Polar Surface Area | 22.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 243.02625 |
| Heavy Atoms | 16 |
| Complexity | 556.60016 |
Chemical Identifiers
| CAS Number | 478079-31-1 |
|---|---|
| SMILES | CN1C=C(C2=CC=CC=C21)C(=O)C(F)(F)Cl |
Product Overview
2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone (CAS 478079-31-1), with molecular formula C11H8ClF2NO and molecular weight 243.03 g/mol. IUPAC: 2-chloro-2,2-difluoro-1-(1-methylindol-3-yl)ethanone.
Chemical Property Profile of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone
Property Insights of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone
The XLogP value of 3.1926 indicates that 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 22.0 Ų, 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone?
The CAS number of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone is 478079-31-1.
What is the molecular formula of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone?
The molecular formula of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone is C11H8ClF2NO.
What is the molecular weight of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone?
The molecular weight of 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone is 243.03 g/mol.
Where can I buy 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone?
You can request a quote for 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone?
Yes, KEHONG BIO provides custom synthesis services for 2-chloro-2,2-difluoro-1-(1-methyl-1H-indol-3-yl)-1-ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.