![(E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one structure](/static/products/4780/478079-01-5.webp)
(E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one
TL;DR: (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one (CAS 478079-01-5) is a chemical compound with molecular formula C23H19ClF3N3OS and molecular weight 477.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-2-phenyl-3-thiophen-2-ylprop-2-en-1-one
Also Known As: (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one, 1-[4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl]-2-phenyl-3-(2-thienyl)-2-propen-1-one, 1-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-2-phenyl-3-thiophen-2-ylprop-2-en-1-one, 1-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-phenyl-3-(thiophen-2-yl)prop-2-en-1-one
| Molecular Formula | C23H19ClF3N3OS |
|---|---|
| Molecular Weight | 477.09 g/mol |
| LogP | 5.7047 |
| Topological Polar Surface Area | 36.44 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 477.08896 |
| Heavy Atoms | 32 |
| Complexity | 1109.2703 |
Chemical Identifiers
| CAS Number | 478079-01-5 |
|---|---|
| SMILES | C1CN(CCN1C2=C(C=C(C=N2)C(F)(F)F)Cl)C(=O)C(=CC3=CC=CS3)C4=CC=CC=C4 |
Product Overview
(E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one (CAS 478079-01-5), with molecular formula C23H19ClF3N3OS and molecular weight 477.09 g/mol. IUPAC: 1-[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-2-phenyl-3-thiophen-2-ylprop-2-en-1-one.
Chemical Property Profile of (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one
Property Insights of (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one
The XLogP value of 5.7047 indicates that (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.44 Ų, (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one?
The CAS number of (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one is 478079-01-5.
What is the molecular formula of (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one?
The molecular formula of (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one is C23H19ClF3N3OS.
What is the molecular weight of (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one?
The molecular weight of (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one is 477.09 g/mol.
Where can I buy (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one?
You can request a quote for (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-1-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-2-phenyl-3-(2-thienyl)-2-propen-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.