2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone
TL;DR: 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone (CAS 478065-02-0) is a chemical compound with molecular formula C10H6ClF2NO and molecular weight 229.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone
Also Known As: 2-chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone, 2-chloro-2,2-difluoro-1-(1H-indol-3-yl)-1-ethanone, 2-chloro-2,2-difluoro-1-(1H-indol-3-yl)ethan-1-one, Ethanone,2-chloro-2,2-difluoro-1- -, Ethanone, 2-chloro-2,2-difluoro-1-(1H-indol-3-yl)- (9CI)
| Molecular Formula | C10H6ClF2NO |
|---|---|
| Molecular Weight | 229.01 g/mol |
| LogP | 3.1822 |
| Topological Polar Surface Area | 32.86 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 229.0106 |
| Heavy Atoms | 15 |
| Complexity | 515.3619 |
Chemical Identifiers
| CAS Number | 478065-02-0 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2)C(=O)C(F)(F)Cl |
Product Overview
2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone (CAS 478065-02-0), with molecular formula C10H6ClF2NO and molecular weight 229.01 g/mol. IUPAC: 2-chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone.
Chemical Property Profile of 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone
Property Insights of 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone
The XLogP value of 3.1822 indicates that 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.86 Ų, 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone?
The CAS number of 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone is 478065-02-0.
What is the molecular formula of 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone?
The molecular formula of 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone is C10H6ClF2NO.
What is the molecular weight of 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone?
The molecular weight of 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone is 229.01 g/mol.
Where can I buy 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone?
You can request a quote for 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.