6R-0343
TL;DR: 6R-0343 (CAS 478064-60-7) is a chemical compound with molecular formula C23H19ClF3N3O2 and molecular weight 461.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-(1,2-dihydrobenzo[e][1]benzofuran-2-yl)methanone
Also Known As: 6R-0343, {4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}(1,2-dihydronaphtho[2,1-b]furan-2-yl)methanone, [4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-(1,2-dihydrobenzo[e][1]benzofuran-2-yl)methanone, 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-{1H,2H-naphtho[2,1-b]furan-2-carbonyl}piperazine
| Molecular Formula | C23H19ClF3N3O2 |
|---|---|
| Molecular Weight | 461.11 g/mol |
| LogP | 4.5593 |
| Topological Polar Surface Area | 45.67 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 461.1118 |
| Heavy Atoms | 32 |
| Complexity | 1192.8104 |
Chemical Identifiers
| CAS Number | 478064-60-7 |
|---|---|
| SMILES | C1CN(CCN1C2=C(C=C(C=N2)C(F)(F)F)Cl)C(=O)C3CC4=C(O3)C=CC5=CC=CC=C45 |
Product Overview
6R-0343 (CAS 478064-60-7), with molecular formula C23H19ClF3N3O2 and molecular weight 461.11 g/mol. IUPAC: [4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-(1,2-dihydrobenzo[e][1]benzofuran-2-yl)methanone.
Chemical Property Profile of 6R-0343
Property Insights of 6R-0343
The XLogP value of 4.5593 indicates that 6R-0343 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.67 Ų, 6R-0343 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6R-0343 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6R-0343?
The CAS number of 6R-0343 is 478064-60-7.
What is the molecular formula of 6R-0343?
The molecular formula of 6R-0343 is C23H19ClF3N3O2.
What is the molecular weight of 6R-0343?
The molecular weight of 6R-0343 is 461.11 g/mol.
Where can I buy 6R-0343?
You can request a quote for 6R-0343 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6R-0343?
Yes, KEHONG BIO provides custom synthesis services for 6R-0343 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.