GNF-Pf-514
TL;DR: GNF-Pf-514 (CAS 478049-39-7) is a chemical compound with molecular formula C19H8F9N3 and molecular weight 449.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-[4-(trifluoromethyl)phenyl]acetonitrile
Also Known As: 2-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-[4-(trifluoromethyl)phenyl]acetonitrile, 5N-054, 2-[5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-yl]-2-[4-(trifluoromethyl)phenyl]acetonitrile, 1,8-Naphthyridine-2-acetonitrile, 5,7-bis(trifluoromethyl)-alpha-[4-(trifluoromethyl)phenyl]- (9CI)
| Molecular Formula | C19H8F9N3 |
|---|---|
| Molecular Weight | 449.06 g/mol |
| LogP | 6.34168 |
| Topological Polar Surface Area | 49.57 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 449.05746 |
| Heavy Atoms | 31 |
| Complexity | 1154.1681 |
Chemical Identifiers
| CAS Number | 478049-39-7 |
|---|---|
| SMILES | C1=CC(=CC=C1C(C#N)C2=NC3=C(C=C2)C(=CC(=N3)C(F)(F)F)C(F)(F)F)C(F)(F)F |
Product Overview
GNF-Pf-514 (CAS 478049-39-7), with molecular formula C19H8F9N3 and molecular weight 449.06 g/mol. IUPAC: 2-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-[4-(trifluoromethyl)phenyl]acetonitrile.
Chemical Property Profile of GNF-Pf-514
Property Insights of GNF-Pf-514
The XLogP value of 6.34168 indicates that GNF-Pf-514 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.57 Ų, GNF-Pf-514 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, GNF-Pf-514 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of GNF-Pf-514?
The CAS number of GNF-Pf-514 is 478049-39-7.
What is the molecular formula of GNF-Pf-514?
The molecular formula of GNF-Pf-514 is C19H8F9N3.
What is the molecular weight of GNF-Pf-514?
The molecular weight of GNF-Pf-514 is 449.06 g/mol.
Where can I buy GNF-Pf-514?
You can request a quote for GNF-Pf-514 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for GNF-Pf-514?
Yes, KEHONG BIO provides custom synthesis services for GNF-Pf-514 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.