6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone
TL;DR: 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone (CAS 478041-39-3) is a chemical compound with molecular formula C16H11ClFNO and molecular weight 287.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-8-fluoro-2-methyl-3-phenyl-1H-quinolin-4-one
Also Known As: 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone, 6-chloro-8-fluoro-2-methyl-3-phenyl-1H-quinolin-4-one, 3R-0877, 6-chloro-8-fluoro-2-methyl-3-phenyl-1,4-dihydroquinolin-4-one, 6-Chloro-8-fluoro-2-methyl-3-phenylquinolin-4(1H)-one
| Molecular Formula | C16H11ClFNO |
|---|---|
| Molecular Weight | 287.05 g/mol |
| LogP | 4.29602 |
| Topological Polar Surface Area | 32.86 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 287.05133 |
| Heavy Atoms | 20 |
| Complexity | 855.72015 |
Chemical Identifiers
| CAS Number | 478041-39-3 |
|---|---|
| SMILES | CC1=C(C(=O)C2=C(N1)C(=CC(=C2)Cl)F)C3=CC=CC=C3 |
Product Overview
6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone (CAS 478041-39-3), with molecular formula C16H11ClFNO and molecular weight 287.05 g/mol. IUPAC: 6-chloro-8-fluoro-2-methyl-3-phenyl-1H-quinolin-4-one.
Chemical Property Profile of 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone
Property Insights of 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone
The XLogP value of 4.29602 indicates that 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.86 Ų, 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone?
The CAS number of 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone is 478041-39-3.
What is the molecular formula of 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone?
The molecular formula of 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone is C16H11ClFNO.
What is the molecular weight of 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone?
The molecular weight of 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone is 287.05 g/mol.
Where can I buy 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone?
You can request a quote for 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone?
Yes, KEHONG BIO provides custom synthesis services for 6-chloro-8-fluoro-2-methyl-3-phenyl-4(1H)-quinolinone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.