(2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone
TL;DR: (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone (CAS 478032-39-2) is a chemical compound with molecular formula C11H10ClNO2S2 and molecular weight 286.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-5-[(4-methylphenyl)sulfonylmethyl]-1,3-thiazole
Also Known As: (2-chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone, 2-chloro-5-(p-tolylsulfonylmethyl)thiazole, 2-chloro-5-[(4-methylphenyl)sulfonylmethyl]-1,3-thiazole, 3P-016, 2-chloro-5-[(4-methylbenzenesulfonyl)methyl]-1,3-thiazole
| Molecular Formula | C11H10ClNO2S2 |
|---|---|
| Molecular Weight | 286.98 g/mol |
| LogP | 3.07882 |
| Topological Polar Surface Area | 47.03 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 286.98416 |
| Heavy Atoms | 17 |
| Complexity | 617.1759 |
Chemical Identifiers
| CAS Number | 478032-39-2 |
|---|---|
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)CC2=CN=C(S2)Cl |
Product Overview
(2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone (CAS 478032-39-2), with molecular formula C11H10ClNO2S2 and molecular weight 286.98 g/mol. IUPAC: 2-chloro-5-[(4-methylphenyl)sulfonylmethyl]-1,3-thiazole.
Chemical Property Profile of (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone
Property Insights of (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone
The XLogP value of 3.07882 indicates that (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.03 Ų, (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone?
The CAS number of (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone is 478032-39-2.
What is the molecular formula of (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone?
The molecular formula of (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone is C11H10ClNO2S2.
What is the molecular weight of (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone?
The molecular weight of (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone is 286.98 g/mol.
Where can I buy (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone?
You can request a quote for (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone?
Yes, KEHONG BIO provides custom synthesis services for (2-Chloro-1,3-thiazol-5-yl)methyl 4-methylphenyl sulfone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.