2R-1142
TL;DR: 2R-1142 (CAS 478029-46-8) is a chemical compound with molecular formula C25H18ClNO3 and molecular weight 415.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
17-[(4-chlorophenyl)methoxy]-17-azapentacyclo[6.6.5.02,7.09,14.015,19]nonadeca-2,4,6,9,11,13-hexaene-16,18-dione
Also Known As: 2R-1142, 17-[(4-chlorobenzyl)oxy]-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2(7),3,5,9(14),10,12-hexaene-16,18-dione, 17-[(4-chlorophenyl)methoxy]-17-azapentacyclo[6.6.5.0^{2,7}.0^{9,14}.0^{15,19}]nonadeca-2(7),3,5,9(14),10,12-hexaene-16,18-dione, 17-[(4-Chlorophenyl)methoxy]-17-azapentacyclo[6.6.5.02,7.09,14.015,19]nonadeca-2,4,6,9,11,13-hexaene-16,18-dione
| Molecular Formula | C25H18ClNO3 |
|---|---|
| Molecular Weight | 415.10 g/mol |
| LogP | 4.6638 |
| Topological Polar Surface Area | 46.61 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 415.09753 |
| Heavy Atoms | 30 |
| Complexity | 1073.5079 |
Chemical Identifiers
| CAS Number | 478029-46-8 |
|---|---|
| SMILES | C1=CC=C2C3C4C(C(C2=C1)C5=CC=CC=C35)C(=O)N(C4=O)OCC6=CC=C(C=C6)Cl |
Product Overview
2R-1142 (CAS 478029-46-8), with molecular formula C25H18ClNO3 and molecular weight 415.10 g/mol. IUPAC: 17-[(4-chlorophenyl)methoxy]-17-azapentacyclo[6.6.5.02,7.09,14.015,19]nonadeca-2,4,6,9,11,13-hexaene-16,18-dione.
Chemical Property Profile of 2R-1142
Property Insights of 2R-1142
The XLogP value of 4.6638 indicates that 2R-1142 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.61 Ų, 2R-1142 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2R-1142 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2R-1142?
The CAS number of 2R-1142 is 478029-46-8.
What is the molecular formula of 2R-1142?
The molecular formula of 2R-1142 is C25H18ClNO3.
What is the molecular weight of 2R-1142?
The molecular weight of 2R-1142 is 415.10 g/mol.
Where can I buy 2R-1142?
You can request a quote for 2R-1142 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2R-1142?
Yes, KEHONG BIO provides custom synthesis services for 2R-1142 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.