VX 759 structure

VX 759

TL;DR: VX 759 (CAS 478025-29-5) is a chemical compound with molecular formula C22H27NO3S and molecular weight 385.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[(4-methylcyclohexanecarbonyl)-propan-2-ylamino]-5-phenylthiophene-2-carboxylic acid

Also Known As: VX 759, thiophene scaffold, 21, VX759, 3-{isopropyl[(Trans-4-Methylcyclohexyl)carbonyl]amino}-5-Phenylthiophene-2-Carboxylic Acid, J2.048.490J

CAS: 478025-29-5
Molecular Formula C22H27NO3S
Molecular Weight 385.17 g/mol
LogP 5.6
Topological Polar Surface Area 85.9 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 5
Exact Mass 385.17117
Heavy Atoms 27
Complexity 524.0

Chemical Identifiers

CAS Number 478025-29-5
SMILES CC1CCC(CC1)C(=O)N(C2=C(SC(=C2)C3=CC=CC=C3)C(=O)O)C(C)C
InChIKey RZXQBIKGWSLVEK-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (3 patents) Pharmaceutical Intermediates (2 patents)

Product Overview

VX 759 (CAS 478025-29-5), with molecular formula C22H27NO3S and molecular weight 385.17 g/mol. IUPAC: 3-[(4-methylcyclohexanecarbonyl)-propan-2-ylamino]-5-phenylthiophene-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of VX 759

XLogP
5.6
TPSA (Topological Polar Surface Area)
85.9
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
5
Heavy Atoms
27
Complexity
524.0
Exact Mass
385.17117
Monoisotopic Mass
385.17117
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of VX 759

The XLogP value of 5.6 indicates that VX 759 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.9 Ų falls within the moderate polarity range, balancing permeability and solubility for VX 759. Following Lipinski's Rule of Five, VX 759 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of VX 759?

The CAS number of VX 759 is 478025-29-5.

What is the molecular formula of VX 759?

The molecular formula of VX 759 is C22H27NO3S.

What is the molecular weight of VX 759?

The molecular weight of VX 759 is 385.17 g/mol.

Where can I buy VX 759?

You can request a quote for VX 759 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for VX 759?

Yes, KEHONG BIO provides custom synthesis services for VX 759 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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