N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide
TL;DR: N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide (CAS 477889-92-2) is a chemical compound with molecular formula C14H10F3IN2O and molecular weight 405.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(5-iodo-3-methyl-2-pyridinyl)-4-(trifluoromethyl)benzamide
Also Known As: N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide, 2R-0690, N-(5-iodo-3-methyl-2-pyridinyl)-4-(trifluoromethyl)benzenecarboxamide, N-(5-Iodo-3-methyl-2-pyridinyl)-4-(trifluoromethyl)benzamide
| Molecular Formula | C14H10F3IN2O |
|---|---|
| Molecular Weight | 405.98 g/mol |
| LogP | 4.26572 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 405.979 |
| Heavy Atoms | 21 |
| Complexity | 668.9096 |
Chemical Identifiers
| CAS Number | 477889-92-2 |
|---|---|
| SMILES | CC1=CC(=CN=C1NC(=O)C2=CC=C(C=C2)C(F)(F)F)I |
Product Overview
N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide (CAS 477889-92-2), with molecular formula C14H10F3IN2O and molecular weight 405.98 g/mol. IUPAC: N-(5-iodo-3-methyl-2-pyridinyl)-4-(trifluoromethyl)benzamide.
Chemical Property Profile of N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide
Property Insights of N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide
The XLogP value of 4.26572 indicates that N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide?
The CAS number of N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide is 477889-92-2.
What is the molecular formula of N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide?
The molecular formula of N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide is C14H10F3IN2O.
What is the molecular weight of N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide?
The molecular weight of N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide is 405.98 g/mol.
Where can I buy N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide?
You can request a quote for N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.