1P-743
TL;DR: 1P-743 (CAS 477869-98-0) is a chemical compound with molecular formula C18H10Cl3F3N4O and molecular weight 459.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3,4-dichloro-N-[6-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-2-pyridinyl]benzamide
Also Known As: 1P-743, 3,4-dichloro-N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)benzamide, 3,4-dichloro-N-[6-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]pyridin-2-yl]benzamide, 3,4-dichloro-N-(6-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino}-2-pyridinyl)benzenecarboxamide
| Molecular Formula | C18H10Cl3F3N4O |
|---|---|
| Molecular Weight | 459.99 g/mol |
| LogP | 6.4515 |
| Topological Polar Surface Area | 66.91 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 459.98724 |
| Heavy Atoms | 29 |
| Complexity | 1076.4573 |
Chemical Identifiers
| CAS Number | 477869-98-0 |
|---|---|
| SMILES | C1=CC(=NC(=C1)NC(=O)C2=CC(=C(C=C2)Cl)Cl)NC3=C(C=C(C=N3)C(F)(F)F)Cl |
Product Overview
1P-743 (CAS 477869-98-0), with molecular formula C18H10Cl3F3N4O and molecular weight 459.99 g/mol. IUPAC: 3,4-dichloro-N-[6-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-2-pyridinyl]benzamide.
Chemical Property Profile of 1P-743
Property Insights of 1P-743
The XLogP value of 6.4515 indicates that 1P-743 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.91 Ų falls within the moderate polarity range, balancing permeability and solubility for 1P-743. Following Lipinski's Rule of Five, 1P-743 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1P-743?
The CAS number of 1P-743 is 477869-98-0.
What is the molecular formula of 1P-743?
The molecular formula of 1P-743 is C18H10Cl3F3N4O.
What is the molecular weight of 1P-743?
The molecular weight of 1P-743 is 459.99 g/mol.
Where can I buy 1P-743?
You can request a quote for 1P-743 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1P-743?
Yes, KEHONG BIO provides custom synthesis services for 1P-743 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.