1K-906 structure

1K-906

TL;DR: 1K-906 (CAS 477864-87-2) is a chemical compound with molecular formula C22H24ClF3N4O3 and molecular weight 484.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-[3-(4-methoxyphenyl)-2-methyl-1,2-oxazolidin-5-yl]methanone

Also Known As: 1K-906, {4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}[3-(4-methoxyphenyl)-2-methyltetrahydro-5-isoxazolyl]methanone, [4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-[3-(4-methoxyphenyl)-2-methyl-1,2-oxazolidin-5-yl]methanone, 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-[3-(4-methoxyphenyl)-2-methyl-1,2-oxazolidine-5-carbonyl]piperazine

CAS: 477864-87-2
Molecular Formula C22H24ClF3N4O3
Molecular Weight 484.15 g/mol
LogP 3.788
Topological Polar Surface Area 58.14 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 4
Exact Mass 484.1489
Heavy Atoms 33
Complexity 997.37085

Chemical Identifiers

CAS Number 477864-87-2
SMILES CN1C(CC(O1)C(=O)N2CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)Cl)C4=CC=C(C=C4)OC

Product Overview

1K-906 (CAS 477864-87-2), with molecular formula C22H24ClF3N4O3 and molecular weight 484.15 g/mol. IUPAC: [4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-[3-(4-methoxyphenyl)-2-methyl-1,2-oxazolidin-5-yl]methanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 1K-906

XLogP
3.788
TPSA (Topological Polar Surface Area)
58.14
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
4
Heavy Atoms
33
Complexity
997.37085
Exact Mass
484.1489
Monoisotopic Mass
484.1489
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1K-906

The XLogP value of 3.788 indicates that 1K-906 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.14 Ų, 1K-906 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1K-906 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1K-906?

The CAS number of 1K-906 is 477864-87-2.

What is the molecular formula of 1K-906?

The molecular formula of 1K-906 is C22H24ClF3N4O3.

What is the molecular weight of 1K-906?

The molecular weight of 1K-906 is 484.15 g/mol.

Where can I buy 1K-906?

You can request a quote for 1K-906 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1K-906?

Yes, KEHONG BIO provides custom synthesis services for 1K-906 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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