1J-021 structure

1J-021

TL;DR: 1J-021 (CAS 477864-64-5) is a chemical compound with molecular formula C18H13ClF3N5O and molecular weight 407.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[6-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-2-pyridinyl]-3-phenylurea

Also Known As: 1J-021, N-(6-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino}-2-pyridinyl)-N'-phenylurea, 3-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-1-phenylurea, 1-[6-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]pyridin-2-yl]-3-phenylurea, N-(6-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-N'-phenylurea

CAS: 477864-64-5
Molecular Formula C18H13ClF3N5O
Molecular Weight 407.08 g/mol
LogP 5.5364
Topological Polar Surface Area 78.94 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 407.07608
Heavy Atoms 28
Complexity 982.45514

Chemical Identifiers

CAS Number 477864-64-5
SMILES C1=CC=C(C=C1)NC(=O)NC2=CC=CC(=N2)NC3=C(C=C(C=N3)C(F)(F)F)Cl

Product Overview

1J-021 (CAS 477864-64-5), with molecular formula C18H13ClF3N5O and molecular weight 407.08 g/mol. IUPAC: 1-[6-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-2-pyridinyl]-3-phenylurea.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 1J-021

XLogP
5.5364
TPSA (Topological Polar Surface Area)
78.94
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
28
Complexity
982.45514
Exact Mass
407.07608
Monoisotopic Mass
407.07608
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1J-021

The XLogP value of 5.5364 indicates that 1J-021 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.94 Ų falls within the moderate polarity range, balancing permeability and solubility for 1J-021. Following Lipinski's Rule of Five, 1J-021 has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1J-021?

The CAS number of 1J-021 is 477864-64-5.

What is the molecular formula of 1J-021?

The molecular formula of 1J-021 is C18H13ClF3N5O.

What is the molecular weight of 1J-021?

The molecular weight of 1J-021 is 407.08 g/mol.

Where can I buy 1J-021?

You can request a quote for 1J-021 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1J-021?

Yes, KEHONG BIO provides custom synthesis services for 1J-021 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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