N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
TL;DR: N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 477864-06-5) is a chemical compound with molecular formula C16H12F6N2O3S and molecular weight 426.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
Also Known As: N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide, N'-[(Z)-2-thienylmethylidene]-2,5-bis(2,2,2-trifluoroethoxy)benzenecarbohydrazide
| Molecular Formula | C16H12F6N2O3S |
|---|---|
| Molecular Weight | 426.05 g/mol |
| LogP | 4.3942 |
| Topological Polar Surface Area | 59.92 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 426.04727 |
| Heavy Atoms | 28 |
| Complexity | 818.77246 |
Chemical Identifiers
| CAS Number | 477864-06-5 |
|---|---|
| SMILES | C1=CSC(=C1)C=NNC(=O)C2=C(C=CC(=C2)OCC(F)(F)F)OCC(F)(F)F |
Product Overview
N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 477864-06-5), with molecular formula C16H12F6N2O3S and molecular weight 426.05 g/mol. IUPAC: N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide.
Chemical Property Profile of N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
Property Insights of N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
The XLogP value of 4.3942 indicates that N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.92 Ų, N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide?
The CAS number of N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide is 477864-06-5.
What is the molecular formula of N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide?
The molecular formula of N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide is C16H12F6N2O3S.
What is the molecular weight of N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide?
The molecular weight of N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide is 426.05 g/mol.
Where can I buy N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide?
You can request a quote for N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide?
Yes, KEHONG BIO provides custom synthesis services for N-(thiophen-2-ylmethylideneamino)-2,5-bis(2,2,2-trifluoroethoxy)benzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.