![4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine structure](/static/products/4778/477862-72-9.webp)
4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine
TL;DR: 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine (CAS 477862-72-9) is a chemical compound with molecular formula C18H16FN3O and molecular weight 309.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[1-(3-fluoro-4-phenylphenoxy)ethyl]pyrimidin-2-amine
Also Known As: Bionet2_000436, 4-{1-[(2-fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine, 4-[1-({2-fluoro-[1,1'-biphenyl]-4-yl}oxy)ethyl]pyrimidin-2-amine, 4-[1-(3-fluoro-4-phenylphenoxy)ethyl]pyrimidin-2-amine, 12P-120
| Molecular Formula | C18H16FN3O |
|---|---|
| Molecular Weight | 309.13 g/mol |
| LogP | 4.0049 |
| Topological Polar Surface Area | 61.03 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 309.12775 |
| Heavy Atoms | 23 |
| Complexity | 808.3719 |
Chemical Identifiers
| CAS Number | 477862-72-9 |
|---|---|
| SMILES | CC(C1=NC(=NC=C1)N)OC2=CC(=C(C=C2)C3=CC=CC=C3)F |
Product Overview
4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine (CAS 477862-72-9), with molecular formula C18H16FN3O and molecular weight 309.13 g/mol. IUPAC: 4-[1-(3-fluoro-4-phenylphenoxy)ethyl]pyrimidin-2-amine.
Chemical Property Profile of 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine
Property Insights of 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine
The XLogP value of 4.0049 indicates that 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.03 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine. Following Lipinski's Rule of Five, 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine?
The CAS number of 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine is 477862-72-9.
What is the molecular formula of 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine?
The molecular formula of 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine is C18H16FN3O.
What is the molecular weight of 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine?
The molecular weight of 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine is 309.13 g/mol.
Where can I buy 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine?
You can request a quote for 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine?
Yes, KEHONG BIO provides custom synthesis services for 4-{1-[(2-Fluoro[1,1'-biphenyl]-4-yl)oxy]ethyl}-2-pyrimidinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.