7-chloro-N-(2-thienylmethyl)-4-quinazolinamine
TL;DR: 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine (CAS 477861-99-7) is a chemical compound with molecular formula C13H10ClN3S and molecular weight 275.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-N-(thiophen-2-ylmethyl)quinazolin-4-amine
Also Known As: 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine, 7-chloro-N-(thiophen-2-ylmethyl)quinazolin-4-amine, 7-chloro-N-[(thiophen-2-yl)methyl]quinazolin-4-amine, 7-chloro-N-(2-thienylmethyl)quinazolin-4-amine
| Molecular Formula | C13H10ClN3S |
|---|---|
| Molecular Weight | 275.03 g/mol |
| LogP | 3.9568 |
| Topological Polar Surface Area | 37.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 275.02838 |
| Heavy Atoms | 18 |
| Complexity | 667.0629 |
Chemical Identifiers
| CAS Number | 477861-99-7 |
|---|---|
| SMILES | C1=CSC(=C1)CNC2=NC=NC3=C2C=CC(=C3)Cl |
Product Overview
7-chloro-N-(2-thienylmethyl)-4-quinazolinamine (CAS 477861-99-7), with molecular formula C13H10ClN3S and molecular weight 275.03 g/mol. IUPAC: 7-chloro-N-(thiophen-2-ylmethyl)quinazolin-4-amine.
Chemical Property Profile of 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine
Property Insights of 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine
The XLogP value of 3.9568 indicates that 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.81 Ų, 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine?
The CAS number of 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine is 477861-99-7.
What is the molecular formula of 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine?
The molecular formula of 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine is C13H10ClN3S.
What is the molecular weight of 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine?
The molecular weight of 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine is 275.03 g/mol.
Where can I buy 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine?
You can request a quote for 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine?
Yes, KEHONG BIO provides custom synthesis services for 7-chloro-N-(2-thienylmethyl)-4-quinazolinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.