![6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine structure](/static/products/4778/477859-89-5.webp)
6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine
TL;DR: 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine (CAS 477859-89-5) is a chemical compound with molecular formula C18H16F3N3O2 and molecular weight 363.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6,7-dimethoxy-N-[[3-(trifluoromethyl)phenyl]methyl]quinazolin-4-amine
Also Known As: Bionet1_003554, 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine, 12N-034, 6,7-dimethoxy-N-[[3-(trifluoromethyl)phenyl]methyl]quinazolin-4-amine, 6,7-dimethoxy-N-{[3-(trifluoromethyl)phenyl]methyl}quinazolin-4-amine
| Molecular Formula | C18H16F3N3O2 |
|---|---|
| Molecular Weight | 363.12 g/mol |
| LogP | 4.2779 |
| Topological Polar Surface Area | 56.27 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 363.11948 |
| Heavy Atoms | 26 |
| Complexity | 929.18866 |
Chemical Identifiers
| CAS Number | 477859-89-5 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NCC3=CC(=CC=C3)C(F)(F)F)OC |
Product Overview
6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine (CAS 477859-89-5), with molecular formula C18H16F3N3O2 and molecular weight 363.12 g/mol. IUPAC: 6,7-dimethoxy-N-[[3-(trifluoromethyl)phenyl]methyl]quinazolin-4-amine.
Chemical Property Profile of 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine
Property Insights of 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine
The XLogP value of 4.2779 indicates that 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.27 Ų, 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine?
The CAS number of 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine is 477859-89-5.
What is the molecular formula of 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine?
The molecular formula of 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine is C18H16F3N3O2.
What is the molecular weight of 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine?
The molecular weight of 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine is 363.12 g/mol.
Where can I buy 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine?
You can request a quote for 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine?
Yes, KEHONG BIO provides custom synthesis services for 6,7-dimethoxy-N-[3-(trifluoromethyl)benzyl]-4-quinazolinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.