11R-0022 structure

11R-0022

TL;DR: 11R-0022 (CAS 477858-76-7) is a chemical compound with molecular formula C24H20Cl2N4OS and molecular weight 482.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7-[1-(2,4-dichlorophenoxy)ethyl]-2-[3-(2,5-dimethylpyrrol-1-yl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidine

Also Known As: 11R-0022, 2,4-DICHLOROPHENYL 1-(2-[3-(2,5-DIMETHYL-1H-PYRROL-1-YL)-2-THIENYL]PYRAZOLO[1,5-A]PYRIMIDIN-7-YL)ETHYL ETHER, 1-(2-{7-[1-(2,4-dichlorophenoxy)ethyl]pyrazolo[1,5-a]pyrimidin-2-yl}thiophen-3-yl)-2,5-dimethyl-1H-pyrrole, 7-[1-(2,4-dichlorophenoxy)ethyl]-2-[3-(2,5-dimethylpyrrol-1-yl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidine, 7-[1-(2,4-dichlorophenoxy)ethyl]-2-[3-(2,5-dimethyl-1H-pyrrol-1-yl)-2-thienyl]pyrazolo[1,5-a]pyrimidine

CAS: 477858-76-7
Molecular Formula C24H20Cl2N4OS
Molecular Weight 482.07 g/mol
LogP 7.31214
Topological Polar Surface Area 44.35 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 5
Exact Mass 482.0735
Heavy Atoms 32
Complexity 1415.8352

Chemical Identifiers

CAS Number 477858-76-7
SMILES CC1=CC=C(N1C2=C(SC=C2)C3=NN4C(=CC=NC4=C3)C(C)OC5=C(C=C(C=C5)Cl)Cl)C

Product Overview

11R-0022 (CAS 477858-76-7), with molecular formula C24H20Cl2N4OS and molecular weight 482.07 g/mol. IUPAC: 7-[1-(2,4-dichlorophenoxy)ethyl]-2-[3-(2,5-dimethylpyrrol-1-yl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 11R-0022

XLogP
7.31214
TPSA (Topological Polar Surface Area)
44.35
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
5
Heavy Atoms
32
Complexity
1415.8352
Exact Mass
482.0735
Monoisotopic Mass
482.0735
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 11R-0022

The XLogP value of 7.31214 indicates that 11R-0022 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.35 Ų, 11R-0022 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 11R-0022 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 11R-0022?

The CAS number of 11R-0022 is 477858-76-7.

What is the molecular formula of 11R-0022?

The molecular formula of 11R-0022 is C24H20Cl2N4OS.

What is the molecular weight of 11R-0022?

The molecular weight of 11R-0022 is 482.07 g/mol.

Where can I buy 11R-0022?

You can request a quote for 11R-0022 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 11R-0022?

Yes, KEHONG BIO provides custom synthesis services for 11R-0022 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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