10R-0258
TL;DR: 10R-0258 (CAS 477848-70-7) is a chemical compound with molecular formula C19H17ClN4O3S2 and molecular weight 448.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(2-chloro-1,3-thiazol-5-yl)methylsulfanyl]-3-(furan-2-ylmethyl)-6,7-dimethoxyquinazolin-4-imine
Also Known As: 10R-0258, 2-{[(2-chloro-1,3-thiazol-5-yl)methyl]sulfanyl}-3-(2-furylmethyl)-6,7-dimethoxy-4(3H)-quinazolinimine, 2-[(2-chloro-1,3-thiazol-5-yl)methylsulfanyl]-3-(furan-2-ylmethyl)-6,7-dimethoxyquinazolin-4-imine, 2-{[(2-chloro-1,3-thiazol-5-yl)methyl]sulfanyl}-3-[(furan-2-yl)methyl]-6,7-dimethoxy-3,4-dihydroquinazolin-4-imine, 2-[(2-chloro-1,3-thiazol-5-yl)methylsulfanyl]-3-(2-furylmethyl)-6,7-dimethoxy-quinazolin-4-imine
| Molecular Formula | C19H17ClN4O3S2 |
|---|---|
| Molecular Weight | 448.04 g/mol |
| LogP | 4.57647 |
| Topological Polar Surface Area | 86.16 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 7 |
| Exact Mass | 448.04306 |
| Heavy Atoms | 29 |
| Complexity | 1204.3591 |
Chemical Identifiers
| CAS Number | 477848-70-7 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(=N)N(C(=N2)SCC3=CN=C(S3)Cl)CC4=CC=CO4)OC |
Product Overview
10R-0258 (CAS 477848-70-7), with molecular formula C19H17ClN4O3S2 and molecular weight 448.04 g/mol. IUPAC: 2-[(2-chloro-1,3-thiazol-5-yl)methylsulfanyl]-3-(furan-2-ylmethyl)-6,7-dimethoxyquinazolin-4-imine.
Chemical Property Profile of 10R-0258
Property Insights of 10R-0258
The XLogP value of 4.57647 indicates that 10R-0258 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.16 Ų falls within the moderate polarity range, balancing permeability and solubility for 10R-0258. Following Lipinski's Rule of Five, 10R-0258 has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10R-0258?
The CAS number of 10R-0258 is 477848-70-7.
What is the molecular formula of 10R-0258?
The molecular formula of 10R-0258 is C19H17ClN4O3S2.
What is the molecular weight of 10R-0258?
The molecular weight of 10R-0258 is 448.04 g/mol.
Where can I buy 10R-0258?
You can request a quote for 10R-0258 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10R-0258?
Yes, KEHONG BIO provides custom synthesis services for 10R-0258 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.