10R-0034
TL;DR: 10R-0034 (CAS 477848-54-7) is a chemical compound with molecular formula C17H8Cl2F3N3S and molecular weight 412.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(3,4-dichlorophenyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Also Known As: 10R-0034, 2-(3,4-dichlorophenyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine, 2-(3,4-dichlorophenyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine, 2-(3,4-dichlorophenyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
| Molecular Formula | C17H8Cl2F3N3S |
|---|---|
| Molecular Weight | 412.98 g/mol |
| LogP | 6.4504 |
| Topological Polar Surface Area | 30.19 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 412.9768 |
| Heavy Atoms | 26 |
| Complexity | 1104.5895 |
Chemical Identifiers
| CAS Number | 477848-54-7 |
|---|---|
| SMILES | C1=CSC(=C1)C2=NC3=CC(=NN3C(=C2)C(F)(F)F)C4=CC(=C(C=C4)Cl)Cl |
Product Overview
10R-0034 (CAS 477848-54-7), with molecular formula C17H8Cl2F3N3S and molecular weight 412.98 g/mol. IUPAC: 2-(3,4-dichlorophenyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine.
Chemical Property Profile of 10R-0034
Property Insights of 10R-0034
The XLogP value of 6.4504 indicates that 10R-0034 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 30.19 Ų, 10R-0034 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 10R-0034 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10R-0034?
The CAS number of 10R-0034 is 477848-54-7.
What is the molecular formula of 10R-0034?
The molecular formula of 10R-0034 is C17H8Cl2F3N3S.
What is the molecular weight of 10R-0034?
The molecular weight of 10R-0034 is 412.98 g/mol.
Where can I buy 10R-0034?
You can request a quote for 10R-0034 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10R-0034?
Yes, KEHONG BIO provides custom synthesis services for 10R-0034 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.