3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine
TL;DR: 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine (CAS 477846-05-2) is a chemical compound with molecular formula C10H6ClF3N2OS and molecular weight 293.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxymethyl]-1,3-thiazole
Also Known As: 3-chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine, 3-chloro-2-[(1,3-thiazol-5-yl)methoxy]-5-(trifluoromethyl)pyridine, 5-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxymethyl]-1,3-thiazole, 5-[[3-chloro-5-(trifluoromethyl)-2-pyridyl]oxymethyl]thiazole, C10H6ClF3N2OS
| Molecular Formula | C10H6ClF3N2OS |
|---|---|
| Molecular Weight | 293.98 g/mol |
| LogP | 3.7893 |
| Topological Polar Surface Area | 35.01 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 293.98416 |
| Heavy Atoms | 18 |
| Complexity | 530.41425 |
Chemical Identifiers
| CAS Number | 477846-05-2 |
|---|---|
| SMILES | C1=C(C=NC(=C1Cl)OCC2=CN=CS2)C(F)(F)F |
Product Overview
3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine (CAS 477846-05-2), with molecular formula C10H6ClF3N2OS and molecular weight 293.98 g/mol. IUPAC: 5-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxymethyl]-1,3-thiazole.
Chemical Property Profile of 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine
Property Insights of 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine
The XLogP value of 3.7893 indicates that 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.01 Ų, 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine?
The CAS number of 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine is 477846-05-2.
What is the molecular formula of 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine?
The molecular formula of 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine is C10H6ClF3N2OS.
What is the molecular weight of 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine?
The molecular weight of 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine is 293.98 g/mol.
Where can I buy 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine?
You can request a quote for 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine?
Yes, KEHONG BIO provides custom synthesis services for 3-Chloro-2-(1,3-thiazol-5-ylmethoxy)-5-(trifluoromethyl)pyridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.