10N-499S
TL;DR: 10N-499S (CAS 477845-71-9) is a chemical compound with molecular formula C18H16N2OS2 and molecular weight 340.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(4-methylphenyl)sulfanylmethyl]-2,3-dihydro-[1,3]thiazolo[2,3-b]quinazolin-5-one
Also Known As: 10N-499S, 3-{[(4-methylphenyl)sulfanyl]methyl}-2,3-dihydro-5H-[1,3]thiazolo[2,3-b]quinazolin-5-one, 3-[(4-methylphenyl)sulfanylmethyl]-2,3-dihydro-[1,3]thiazolo[2,3-b]quinazolin-5-one, 3-{[(4-methylphenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one
| Molecular Formula | C18H16N2OS2 |
|---|---|
| Molecular Weight | 340.07 g/mol |
| LogP | 4.14402 |
| Topological Polar Surface Area | 34.89 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 340.0704 |
| Heavy Atoms | 23 |
| Complexity | 918.44806 |
Chemical Identifiers
| CAS Number | 477845-71-9 |
|---|---|
| SMILES | CC1=CC=C(C=C1)SCC2CSC3=NC4=CC=CC=C4C(=O)N23 |
Product Overview
10N-499S (CAS 477845-71-9), with molecular formula C18H16N2OS2 and molecular weight 340.07 g/mol. IUPAC: 3-[(4-methylphenyl)sulfanylmethyl]-2,3-dihydro-[1,3]thiazolo[2,3-b]quinazolin-5-one.
Chemical Property Profile of 10N-499S
Property Insights of 10N-499S
The XLogP value of 4.14402 indicates that 10N-499S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.89 Ų, 10N-499S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 10N-499S has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10N-499S?
The CAS number of 10N-499S is 477845-71-9.
What is the molecular formula of 10N-499S?
The molecular formula of 10N-499S is C18H16N2OS2.
What is the molecular weight of 10N-499S?
The molecular weight of 10N-499S is 340.07 g/mol.
Where can I buy 10N-499S?
You can request a quote for 10N-499S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10N-499S?
Yes, KEHONG BIO provides custom synthesis services for 10N-499S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.