N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide
TL;DR: N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide (CAS 477768-24-4) is a chemical compound with molecular formula C16H14F2N2O2S and molecular weight 336.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2,4-difluorophenyl)-5-oxo-1-(thiophen-2-ylmethyl)pyrrolidine-2-carboxamide
Also Known As: 4P-518S, N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide, N-(2,4-difluorophenyl)-5-oxo-1-(thiophen-2-ylmethyl)pyrrolidine-2-carboxamide, N-(2,4-difluorophenyl)-5-oxo-1-[(thiophen-2-yl)methyl]pyrrolidine-2-carboxamide
| Molecular Formula | C16H14F2N2O2S |
|---|---|
| Molecular Weight | 336.07 g/mol |
| LogP | 3.156 |
| Topological Polar Surface Area | 49.41 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 336.0744 |
| Heavy Atoms | 23 |
| Complexity | 733.6864 |
Chemical Identifiers
| CAS Number | 477768-24-4 |
|---|---|
| SMILES | C1CC(=O)N(C1C(=O)NC2=C(C=C(C=C2)F)F)CC3=CC=CS3 |
Product Overview
N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide (CAS 477768-24-4), with molecular formula C16H14F2N2O2S and molecular weight 336.07 g/mol. IUPAC: N-(2,4-difluorophenyl)-5-oxo-1-(thiophen-2-ylmethyl)pyrrolidine-2-carboxamide.
Chemical Property Profile of N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide
Property Insights of N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide
The XLogP value of 3.156 indicates that N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.41 Ų, N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide?
The CAS number of N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide is 477768-24-4.
What is the molecular formula of N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide?
The molecular formula of N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide is C16H14F2N2O2S.
What is the molecular weight of N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide?
The molecular weight of N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide is 336.07 g/mol.
Where can I buy N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide?
You can request a quote for N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(2,4-difluorophenyl)-5-oxo-1-(2-thienylmethyl)-2-pyrrolidinecarboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.