12K-522S structure

12K-522S

TL;DR: 12K-522S (CAS 477709-52-7) is a chemical compound with molecular formula C18H19ClN4O2S and molecular weight 390.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6-[(4-chlorophenyl)sulfinylmethyl]-N,N-dimethyl-2-pyridin-2-ylpyrimidin-4-amine;hydrate

Also Known As: 12K-522S, 6-[(4-chlorobenzenesulfinyl)methyl]-N,N-dimethyl-2-(pyridin-2-yl)pyrimidin-4-amine hydrate, 6-[(4-chlorophenyl)sulfinylmethyl]-N,N-dimethyl-2-pyridin-2-ylpyrimidin-4-amine;hydrate, 6-[(4-chlorophenyl)sulfinylmethyl]-N,N-dimethyl-2-pyridin-2-yl-pyrimidin-4-amine Hydrate, 6-[(4-chlorophenyl)sulfinylmethyl]-N,N-dimethyl-2-pyridin-2-ylpyrimidin-4-amine hydrate

CAS: 477709-52-7
Molecular Formula C18H19ClN4O2S
Molecular Weight 390.09 g/mol
LogP 2.7411
Topological Polar Surface Area 90.48 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 5
Exact Mass 390.09174
Heavy Atoms 26
Complexity 889.45276

Chemical Identifiers

CAS Number 477709-52-7
SMILES CN(C)C1=NC(=NC(=C1)CS(=O)C2=CC=C(C=C2)Cl)C3=CC=CC=N3.O

Product Overview

12K-522S (CAS 477709-52-7), with molecular formula C18H19ClN4O2S and molecular weight 390.09 g/mol. IUPAC: 6-[(4-chlorophenyl)sulfinylmethyl]-N,N-dimethyl-2-pyridin-2-ylpyrimidin-4-amine;hydrate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 12K-522S

XLogP
2.7411
TPSA (Topological Polar Surface Area)
90.48
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
5
Heavy Atoms
26
Complexity
889.45276
Exact Mass
390.09174
Monoisotopic Mass
390.09174
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 12K-522S

The XLogP value of 2.7411 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 12K-522S. The TPSA of 90.48 Ų falls within the moderate polarity range, balancing permeability and solubility for 12K-522S. Following Lipinski's Rule of Five, 12K-522S has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 12K-522S?

The CAS number of 12K-522S is 477709-52-7.

What is the molecular formula of 12K-522S?

The molecular formula of 12K-522S is C18H19ClN4O2S.

What is the molecular weight of 12K-522S?

The molecular weight of 12K-522S is 390.09 g/mol.

Where can I buy 12K-522S?

You can request a quote for 12K-522S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 12K-522S?

Yes, KEHONG BIO provides custom synthesis services for 12K-522S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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