AF-399/40850624 structure

AF-399/40850624

TL;DR: AF-399/40850624 (CAS 477555-72-9) is a chemical compound with molecular formula C19H18N2O3S and molecular weight 354.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide

Also Known As: AF-399/40850624, F0882-0488, N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamide, N-{3-cyano-4H,5H,6H,7H,8H-cyclohepta[b]thiophen-2-yl}-2,3-dihydro-1,4-benzodioxine-6-carboxamide, N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide

CAS: 477555-72-9
Molecular Formula C19H18N2O3S
Molecular Weight 354.10 g/mol
LogP 3.91218
Topological Polar Surface Area 71.35 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 2
Exact Mass 354.10382
Heavy Atoms 25
Complexity 866.28467

Chemical Identifiers

CAS Number 477555-72-9
SMILES C1CCC2=C(CC1)SC(=C2C#N)NC(=O)C3=CC4=C(C=C3)OCCO4

Product Overview

AF-399/40850624 (CAS 477555-72-9), with molecular formula C19H18N2O3S and molecular weight 354.10 g/mol. IUPAC: N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AF-399/40850624

XLogP
3.91218
TPSA (Topological Polar Surface Area)
71.35
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
2
Heavy Atoms
25
Complexity
866.28467
Exact Mass
354.10382
Monoisotopic Mass
354.10382
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AF-399/40850624

The XLogP value of 3.91218 indicates that AF-399/40850624 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.35 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/40850624. Following Lipinski's Rule of Five, AF-399/40850624 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AF-399/40850624?

The CAS number of AF-399/40850624 is 477555-72-9.

What is the molecular formula of AF-399/40850624?

The molecular formula of AF-399/40850624 is C19H18N2O3S.

What is the molecular weight of AF-399/40850624?

The molecular weight of AF-399/40850624 is 354.10 g/mol.

Where can I buy AF-399/40850624?

You can request a quote for AF-399/40850624 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AF-399/40850624?

Yes, KEHONG BIO provides custom synthesis services for AF-399/40850624 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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