2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone structure

2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone

TL;DR: 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone (CAS 477329-76-3) is a chemical compound with molecular formula C21H14BrFN4OS and molecular weight 468.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[[4-(4-bromophenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-fluorophenyl)ethanone

Also Known As: 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-fluorophenyl)ethanone, 2-{[4-(4-bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-fluorophenyl)ethanone, 2-((4-(4-BR-PH)-5-(4-PYRIDINYL)-4H-1,2,4-TRIAZOL-3-YL)THIO)-1-(4-F-PH)ETHANONE, 2-[[4-(4-bromophenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-fluorophenyl)ethanone, 2-{[4-(4-BROMOPHENYL)-5-(PYRIDIN-4-YL)-1,2,4-TRIAZOL-3-YL]SULFANYL}-1-(4-FLUOROPHENYL)ETHANONE

CAS: 477329-76-3
Molecular Formula C21H14BrFN4OS
Molecular Weight 468.01 g/mol
LogP 5.2059
Topological Polar Surface Area 60.67 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 6
Exact Mass 468.00558
Heavy Atoms 29
Complexity 1131.827

Chemical Identifiers

CAS Number 477329-76-3
SMILES C1=CC(=CC=C1C(=O)CSC2=NN=C(N2C3=CC=C(C=C3)Br)C4=CC=NC=C4)F

Product Overview

2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone (CAS 477329-76-3), with molecular formula C21H14BrFN4OS and molecular weight 468.01 g/mol. IUPAC: 2-[[4-(4-bromophenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-fluorophenyl)ethanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone

XLogP
5.2059
TPSA (Topological Polar Surface Area)
60.67
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
6
Heavy Atoms
29
Complexity
1131.827
Exact Mass
468.00558
Monoisotopic Mass
468.00558
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone

The XLogP value of 5.2059 indicates that 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.67 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone. Following Lipinski's Rule of Five, 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone?

The CAS number of 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone is 477329-76-3.

What is the molecular formula of 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone?

The molecular formula of 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone is C21H14BrFN4OS.

What is the molecular weight of 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone?

The molecular weight of 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone is 468.01 g/mol.

Where can I buy 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone?

You can request a quote for 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone?

Yes, KEHONG BIO provides custom synthesis services for 2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-YL)thio)-1-(4-F-PH)ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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