F0837-0657 structure

F0837-0657

TL;DR: F0837-0657 (CAS 477305-32-1) is a chemical compound with molecular formula C22H13BrN4O3S and molecular weight 491.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-[[(E)-2-[4-(6-bromo-2-oxochromen-3-yl)-1,3-thiazol-2-yl]-2-cyanoethenyl]amino]benzamide

Also Known As: F0837-0657, 4-{[(1E)-2-[4-(6-bromo-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]-2-cyanoeth-1-en-1-yl]amino}benzamide, (E)-4-((2-(4-(6-bromo-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-2-cyanovinyl)amino)benzamide, 4-[[(E)-2-[4-(6-bromo-2-oxochromen-3-yl)-1,3-thiazol-2-yl]-2-cyanoethenyl]amino]benzamide, 4-((2-(4-(6-Bromo-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-2-cyanovinyl)amino)benzamide

CAS: 477305-32-1
Molecular Formula C22H13BrN4O3S
Molecular Weight 491.99 g/mol
LogP 4.75448
Topological Polar Surface Area 122.01 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 491.98917
Heavy Atoms 31
Complexity 1431.911

Chemical Identifiers

CAS Number 477305-32-1
SMILES C1=CC(=CC=C1C(=O)N)N/C=C(\C#N)/C2=NC(=CS2)C3=CC4=C(C=CC(=C4)Br)OC3=O

Product Overview

F0837-0657 (CAS 477305-32-1), with molecular formula C22H13BrN4O3S and molecular weight 491.99 g/mol. IUPAC: 4-[[(E)-2-[4-(6-bromo-2-oxochromen-3-yl)-1,3-thiazol-2-yl]-2-cyanoethenyl]amino]benzamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of F0837-0657

XLogP
4.75448
TPSA (Topological Polar Surface Area)
122.01
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
31
Complexity
1431.911
Exact Mass
491.98917
Monoisotopic Mass
491.98917
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F0837-0657

The XLogP value of 4.75448 indicates that F0837-0657 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 122.01 Ų falls within the moderate polarity range, balancing permeability and solubility for F0837-0657. Following Lipinski's Rule of Five, F0837-0657 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F0837-0657?

The CAS number of F0837-0657 is 477305-32-1.

What is the molecular formula of F0837-0657?

The molecular formula of F0837-0657 is C22H13BrN4O3S.

What is the molecular weight of F0837-0657?

The molecular weight of F0837-0657 is 491.99 g/mol.

Where can I buy F0837-0657?

You can request a quote for F0837-0657 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F0837-0657?

Yes, KEHONG BIO provides custom synthesis services for F0837-0657 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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