F0837-0629 structure

F0837-0629

TL;DR: F0837-0629 (CAS 477305-22-9) is a chemical compound with molecular formula C19H10ClF3N4O2S and molecular weight 450.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(E)-3-[4-chloro-3-(trifluoromethyl)anilino]-2-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile

Also Known As: F0837-0629, (2E)-3-{[4-chloro-3-(trifluoromethyl)phenyl]amino}-2-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile, (E)-3-((4-chloro-3-(trifluoromethyl)phenyl)amino)-2-(4-(4-nitrophenyl)thiazol-2-yl)acrylonitrile, (E)-3-[4-chloro-3-(trifluoromethyl)anilino]-2-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile

CAS: 477305-22-9
Molecular Formula C19H10ClF3N4O2S
Molecular Weight 450.02 g/mol
LogP 6.36708
Topological Polar Surface Area 91.85 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 5
Exact Mass 450.0165
Heavy Atoms 30
Complexity 1167.758

Chemical Identifiers

CAS Number 477305-22-9
SMILES C1=CC(=CC=C1C2=CSC(=N2)/C(=C/NC3=CC(=C(C=C3)Cl)C(F)(F)F)/C#N)[N+](=O)[O-]

Product Overview

F0837-0629 (CAS 477305-22-9), with molecular formula C19H10ClF3N4O2S and molecular weight 450.02 g/mol. IUPAC: (E)-3-[4-chloro-3-(trifluoromethyl)anilino]-2-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of F0837-0629

XLogP
6.36708
TPSA (Topological Polar Surface Area)
91.85
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
5
Heavy Atoms
30
Complexity
1167.758
Exact Mass
450.0165
Monoisotopic Mass
450.0165
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F0837-0629

The XLogP value of 6.36708 indicates that F0837-0629 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 91.85 Ų falls within the moderate polarity range, balancing permeability and solubility for F0837-0629. Following Lipinski's Rule of Five, F0837-0629 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F0837-0629?

The CAS number of F0837-0629 is 477305-22-9.

What is the molecular formula of F0837-0629?

The molecular formula of F0837-0629 is C19H10ClF3N4O2S.

What is the molecular weight of F0837-0629?

The molecular weight of F0837-0629 is 450.02 g/mol.

Where can I buy F0837-0629?

You can request a quote for F0837-0629 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F0837-0629?

Yes, KEHONG BIO provides custom synthesis services for F0837-0629 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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