F0837-0617
TL;DR: F0837-0617 (CAS 477305-10-5) is a chemical compound with molecular formula C19H10Cl2F3N3S and molecular weight 438.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-[4-chloro-3-(trifluoromethyl)anilino]prop-2-enenitrile
Also Known As: F0837-0617, (2E)-3-{[4-chloro-3-(trifluoromethyl)phenyl]amino}-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile, (E)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-[4-chloro-3-(trifluoromethyl)anilino]prop-2-enenitrile, (E)-3-((4-chloro-3-(trifluoromethyl)phenyl)amino)-2-(4-(4-chlorophenyl)thiazol-2-yl)acrylonitrile
| Molecular Formula | C19H10Cl2F3N3S |
|---|---|
| Molecular Weight | 438.99 g/mol |
| LogP | 7.11228 |
| Topological Polar Surface Area | 48.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 438.99246 |
| Heavy Atoms | 28 |
| Complexity | 1067.2633 |
Chemical Identifiers
| CAS Number | 477305-10-5 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=CSC(=N2)/C(=C/NC3=CC(=C(C=C3)Cl)C(F)(F)F)/C#N)Cl |
Product Overview
F0837-0617 (CAS 477305-10-5), with molecular formula C19H10Cl2F3N3S and molecular weight 438.99 g/mol. IUPAC: (E)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-[4-chloro-3-(trifluoromethyl)anilino]prop-2-enenitrile.
Chemical Property Profile of F0837-0617
Property Insights of F0837-0617
The XLogP value of 7.11228 indicates that F0837-0617 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.71 Ų, F0837-0617 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0837-0617 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0837-0617?
The CAS number of F0837-0617 is 477305-10-5.
What is the molecular formula of F0837-0617?
The molecular formula of F0837-0617 is C19H10Cl2F3N3S.
What is the molecular weight of F0837-0617?
The molecular weight of F0837-0617 is 438.99 g/mol.
Where can I buy F0837-0617?
You can request a quote for F0837-0617 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0837-0617?
Yes, KEHONG BIO provides custom synthesis services for F0837-0617 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.