![(2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile structure](/static/products/477/477298-80-9.png)
(2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile
TL;DR: (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile (CAS 477298-80-9) is a chemical compound with molecular formula C19H11BrF3N3S and molecular weight 448.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-[2-(trifluoromethyl)anilino]prop-2-enenitrile
Also Known As: (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile, F0837-0569, (E)-2-(4-(4-bromophenyl)thiazol-2-yl)-3-((2-(trifluoromethyl)phenyl)amino)acrylonitrile, (E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-[2-(trifluoromethyl)anilino]prop-2-enenitrile, 2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-[[2-(trifluoromethyl)phenyl]amino]prop-2-enenitrile
| Molecular Formula | C19H11BrF3N3S |
|---|---|
| Molecular Weight | 448.98 g/mol |
| LogP | 6.56798 |
| Topological Polar Surface Area | 48.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 448.98093 |
| Heavy Atoms | 27 |
| Complexity | 1017.66943 |
Chemical Identifiers
| CAS Number | 477298-80-9 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C(F)(F)F)N/C=C(\C#N)/C2=NC(=CS2)C3=CC=C(C=C3)Br |
Product Overview
(2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile (CAS 477298-80-9), with molecular formula C19H11BrF3N3S and molecular weight 448.98 g/mol. IUPAC: (E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-[2-(trifluoromethyl)anilino]prop-2-enenitrile.
Chemical Property Profile of (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile
Property Insights of (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile
The XLogP value of 6.56798 indicates that (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.71 Ų, (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile?
The CAS number of (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile is 477298-80-9.
What is the molecular formula of (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile?
The molecular formula of (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile is C19H11BrF3N3S.
What is the molecular weight of (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile?
The molecular weight of (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile is 448.98 g/mol.
Where can I buy (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile?
You can request a quote for (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile?
Yes, KEHONG BIO provides custom synthesis services for (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-{[2-(trifluoromethyl)phenyl]amino}prop-2-enenitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.