F0837-0425
TL;DR: F0837-0425 (CAS 477297-73-7) is a chemical compound with molecular formula C19H13BrFN3S and molecular weight 413.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-(2-fluoro-5-methylanilino)prop-2-enenitrile
Also Known As: F0837-0425, (E)-2-(4-(4-bromophenyl)thiazol-2-yl)-3-((2-fluoro-5-methylphenyl)amino)acrylonitrile, (2E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-[(2-fluoro-5-methylphenyl)amino]prop-2-enenitrile, (E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-(2-fluoro-5-methylanilino)prop-2-enenitrile, 2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-[(2-fluoro-5-methyl-phenyl)amino]prop-2-enenitrile
| Molecular Formula | C19H13BrFN3S |
|---|---|
| Molecular Weight | 413.00 g/mol |
| LogP | 5.9967 |
| Topological Polar Surface Area | 48.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 412.99976 |
| Heavy Atoms | 25 |
| Complexity | 971.07947 |
Chemical Identifiers
| CAS Number | 477297-73-7 |
|---|---|
| SMILES | CC1=CC(=C(C=C1)F)N/C=C(\C#N)/C2=NC(=CS2)C3=CC=C(C=C3)Br |
Product Overview
F0837-0425 (CAS 477297-73-7), with molecular formula C19H13BrFN3S and molecular weight 413.00 g/mol. IUPAC: (E)-2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-(2-fluoro-5-methylanilino)prop-2-enenitrile.
Chemical Property Profile of F0837-0425
Property Insights of F0837-0425
The XLogP value of 5.9967 indicates that F0837-0425 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.71 Ų, F0837-0425 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0837-0425 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0837-0425?
The CAS number of F0837-0425 is 477297-73-7.
What is the molecular formula of F0837-0425?
The molecular formula of F0837-0425 is C19H13BrFN3S.
What is the molecular weight of F0837-0425?
The molecular weight of F0837-0425 is 413.00 g/mol.
Where can I buy F0837-0425?
You can request a quote for F0837-0425 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0837-0425?
Yes, KEHONG BIO provides custom synthesis services for F0837-0425 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.