F0837-0405
TL;DR: F0837-0405 (CAS 477297-60-2) is a chemical compound with molecular formula C19H12Cl2FN3S and molecular weight 403.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-3-(3-fluoro-4-methylanilino)prop-2-enenitrile
Also Known As: F0837-0405, (E)-2-(4-(3,4-dichlorophenyl)thiazol-2-yl)-3-((3-fluoro-4-methylphenyl)amino)acrylonitrile, (2E)-2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-3-[(3-fluoro-4-methylphenyl)amino]prop-2-enenitrile, (E)-2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-3-(3-fluoro-4-methylanilino)prop-2-enenitrile
| Molecular Formula | C19H12Cl2FN3S |
|---|---|
| Molecular Weight | 403.01 g/mol |
| LogP | 6.541 |
| Topological Polar Surface Area | 48.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 403.0113 |
| Heavy Atoms | 26 |
| Complexity | 1037.5038 |
Chemical Identifiers
| CAS Number | 477297-60-2 |
|---|---|
| SMILES | CC1=C(C=C(C=C1)N/C=C(\C#N)/C2=NC(=CS2)C3=CC(=C(C=C3)Cl)Cl)F |
Product Overview
F0837-0405 (CAS 477297-60-2), with molecular formula C19H12Cl2FN3S and molecular weight 403.01 g/mol. IUPAC: (E)-2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-3-(3-fluoro-4-methylanilino)prop-2-enenitrile.
Chemical Property Profile of F0837-0405
Property Insights of F0837-0405
The XLogP value of 6.541 indicates that F0837-0405 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.71 Ų, F0837-0405 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0837-0405 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0837-0405?
The CAS number of F0837-0405 is 477297-60-2.
What is the molecular formula of F0837-0405?
The molecular formula of F0837-0405 is C19H12Cl2FN3S.
What is the molecular weight of F0837-0405?
The molecular weight of F0837-0405 is 403.01 g/mol.
Where can I buy F0837-0405?
You can request a quote for F0837-0405 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0837-0405?
Yes, KEHONG BIO provides custom synthesis services for F0837-0405 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.