![(2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile structure](/static/products/477/477297-32-8.png)
(2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile
TL;DR: (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile (CAS 477297-32-8) is a chemical compound with molecular formula C22H13F2N3S and molecular weight 389.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-3-(2,4-difluoroanilino)-2-(4-naphthalen-2-yl-1,3-thiazol-2-yl)prop-2-enenitrile
Also Known As: (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile, (Z)-3-((2,4-difluorophenyl)amino)-2-(4-(naphthalen-2-yl)thiazol-2-yl)acrylonitrile, (Z)-3-(2,4-difluoroanilino)-2-(4-naphthalen-2-yl-1,3-thiazol-2-yl)prop-2-enenitrile
| Molecular Formula | C22H13F2N3S |
|---|---|
| Molecular Weight | 389.08 g/mol |
| LogP | 6.21808 |
| Topological Polar Surface Area | 48.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 389.07983 |
| Heavy Atoms | 28 |
| Complexity | 1237.9996 |
Chemical Identifiers
| CAS Number | 477297-32-8 |
|---|---|
| SMILES | C1=CC=C2C=C(C=CC2=C1)C3=CSC(=N3)/C(=C\NC4=C(C=C(C=C4)F)F)/C#N |
Product Overview
(2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile (CAS 477297-32-8), with molecular formula C22H13F2N3S and molecular weight 389.08 g/mol. IUPAC: (Z)-3-(2,4-difluoroanilino)-2-(4-naphthalen-2-yl-1,3-thiazol-2-yl)prop-2-enenitrile.
Chemical Property Profile of (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile
Property Insights of (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile
The XLogP value of 6.21808 indicates that (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.71 Ų, (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile?
The CAS number of (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile is 477297-32-8.
What is the molecular formula of (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile?
The molecular formula of (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile is C22H13F2N3S.
What is the molecular weight of (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile?
The molecular weight of (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile is 389.08 g/mol.
Where can I buy (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile?
You can request a quote for (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile?
Yes, KEHONG BIO provides custom synthesis services for (2Z)-3-[(2,4-difluorophenyl)amino]-2-[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.