F0837-0372
TL;DR: F0837-0372 (CAS 477297-29-3) is a chemical compound with molecular formula C21H11F2N3O2S and molecular weight 407.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(2,4-difluoroanilino)-2-[4-(2-oxochromen-3-yl)-1,3-thiazol-2-yl]prop-2-enenitrile
Also Known As: F0837-0372, (2E)-3-[(2,4-difluorophenyl)amino]-2-[4-(2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]prop-2-enenitrile, (E)-3-((2,4-difluorophenyl)amino)-2-(4-(2-oxo-2H-chromen-3-yl)thiazol-2-yl)acrylonitrile, (E)-3-(2,4-difluoroanilino)-2-[4-(2-oxochromen-3-yl)-1,3-thiazol-2-yl]prop-2-enenitrile, 3-((2,4-Difluorophenyl)amino)-2-(4-(2-oxo-2H-chromen-3-yl)thiazol-2-yl)acrylonitrile
| Molecular Formula | C21H11F2N3O2S |
|---|---|
| Molecular Weight | 407.05 g/mol |
| LogP | 5.17128 |
| Topological Polar Surface Area | 78.92 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 407.05402 |
| Heavy Atoms | 29 |
| Complexity | 1352.0428 |
Chemical Identifiers
| CAS Number | 477297-29-3 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CSC(=N3)/C(=C/NC4=C(C=C(C=C4)F)F)/C#N |
Product Overview
F0837-0372 (CAS 477297-29-3), with molecular formula C21H11F2N3O2S and molecular weight 407.05 g/mol. IUPAC: (E)-3-(2,4-difluoroanilino)-2-[4-(2-oxochromen-3-yl)-1,3-thiazol-2-yl]prop-2-enenitrile.
Chemical Property Profile of F0837-0372
Property Insights of F0837-0372
The XLogP value of 5.17128 indicates that F0837-0372 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.92 Ų falls within the moderate polarity range, balancing permeability and solubility for F0837-0372. Following Lipinski's Rule of Five, F0837-0372 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0837-0372?
The CAS number of F0837-0372 is 477297-29-3.
What is the molecular formula of F0837-0372?
The molecular formula of F0837-0372 is C21H11F2N3O2S.
What is the molecular weight of F0837-0372?
The molecular weight of F0837-0372 is 407.05 g/mol.
Where can I buy F0837-0372?
You can request a quote for F0837-0372 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0837-0372?
Yes, KEHONG BIO provides custom synthesis services for F0837-0372 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.