F0837-0220 structure

F0837-0220

TL;DR: F0837-0220 (CAS 477296-24-5) is a chemical compound with molecular formula C28H24N2O2S and molecular weight 452.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(E)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-3-(3-methoxy-4-phenylmethoxyphenyl)prop-2-enenitrile

Also Known As: F0837-0220, (E)-3-(4-(benzyloxy)-3-methoxyphenyl)-2-(4-(3,4-dimethylphenyl)thiazol-2-yl)acrylonitrile, (2E)-3-[4-(benzyloxy)-3-methoxyphenyl]-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]prop-2-enenitrile, (E)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-3-(3-methoxy-4-phenylmethoxyphenyl)prop-2-enenitrile, 2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-3-(3-methoxy-4-phenylmethoxy-phenyl)prop-2-enenitrile

CAS: 477296-24-5
Molecular Formula C28H24N2O2S
Molecular Weight 452.16 g/mol
LogP 7.07872
Topological Polar Surface Area 55.14 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 7
Exact Mass 452.15585
Heavy Atoms 33
Complexity 1333.7671

Chemical Identifiers

CAS Number 477296-24-5
SMILES CC1=C(C=C(C=C1)C2=CSC(=N2)/C(=C/C3=CC(=C(C=C3)OCC4=CC=CC=C4)OC)/C#N)C

Product Overview

F0837-0220 (CAS 477296-24-5), with molecular formula C28H24N2O2S and molecular weight 452.16 g/mol. IUPAC: (E)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-3-(3-methoxy-4-phenylmethoxyphenyl)prop-2-enenitrile.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of F0837-0220

XLogP
7.07872
TPSA (Topological Polar Surface Area)
55.14
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
7
Heavy Atoms
33
Complexity
1333.7671
Exact Mass
452.15585
Monoisotopic Mass
452.15585
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F0837-0220

The XLogP value of 7.07872 indicates that F0837-0220 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.14 Ų, F0837-0220 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0837-0220 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F0837-0220?

The CAS number of F0837-0220 is 477296-24-5.

What is the molecular formula of F0837-0220?

The molecular formula of F0837-0220 is C28H24N2O2S.

What is the molecular weight of F0837-0220?

The molecular weight of F0837-0220 is 452.16 g/mol.

Where can I buy F0837-0220?

You can request a quote for F0837-0220 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F0837-0220?

Yes, KEHONG BIO provides custom synthesis services for F0837-0220 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?