5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one
TL;DR: 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one (CAS 477288-48-5) is a chemical compound with molecular formula C21H23N3OS and molecular weight 365.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-benzyl-2-[4-(4-methylphenyl)piperazin-1-yl]-1,3-thiazol-4-one
Also Known As: 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one, 5-benzyl-2-[4-(4-methylphenyl)piperazin-1-yl]-1,3-thiazol-4-one, 5-benzyl-2-[4-(4-methylphenyl)piperazin-1-yl]-4,5-dihydro-1,3-thiazol-4-one
| Molecular Formula | C21H23N3OS |
|---|---|
| Molecular Weight | 365.16 g/mol |
| LogP | 3.35772 |
| Topological Polar Surface Area | 35.91 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 365.1562 |
| Heavy Atoms | 26 |
| Complexity | 795.76575 |
Chemical Identifiers
| CAS Number | 477288-48-5 |
|---|---|
| SMILES | CC1=CC=C(C=C1)N2CCN(CC2)C3=NC(=O)C(S3)CC4=CC=CC=C4 |
Product Overview
5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one (CAS 477288-48-5), with molecular formula C21H23N3OS and molecular weight 365.16 g/mol. IUPAC: 5-benzyl-2-[4-(4-methylphenyl)piperazin-1-yl]-1,3-thiazol-4-one.
Chemical Property Profile of 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one
Property Insights of 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one
The XLogP value of 3.35772 indicates that 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.91 Ų, 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one?
The CAS number of 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one is 477288-48-5.
What is the molecular formula of 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one?
The molecular formula of 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one is C21H23N3OS.
What is the molecular weight of 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one?
The molecular weight of 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one is 365.16 g/mol.
Where can I buy 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one?
You can request a quote for 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 5-benzyl-2-(4-(p-tolyl)piperazin-1-yl)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.