(E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide structure

(E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide

TL;DR: (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide (CAS 477188-75-3) is a chemical compound with molecular formula C20H18N4O2S and molecular weight 378.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2E)-4-(4-ethoxyphenyl)-N-(2-methoxyanilino)-1,3-thiazole-2-carboximidoyl cyanide

Also Known As: (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide, F0760-2345, (E)-4-(4-ethoxyphenyl)-N-(2-methoxyphenyl)-1,3-thiazole-2-carbohydrazonoyl cyanide, (2E)-4-(4-ethoxyphenyl)-N-(2-methoxyanilino)-1,3-thiazole-2-carboximidoyl cyanide, (2E)-[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl][2-(2-methoxyphenyl)hydrazinylidene]ethanenitrile

CAS: 477188-75-3
Molecular Formula C20H18N4O2S
Molecular Weight 378.12 g/mol
LogP 4.55718
Topological Polar Surface Area 79.53 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 7
Exact Mass 378.11505
Heavy Atoms 27
Complexity 974.14685

Chemical Identifiers

CAS Number 477188-75-3
SMILES CCOC1=CC=C(C=C1)C2=CSC(=N2)/C(=N/NC3=CC=CC=C3OC)/C#N

Product Overview

(E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide (CAS 477188-75-3), with molecular formula C20H18N4O2S and molecular weight 378.12 g/mol. IUPAC: (2E)-4-(4-ethoxyphenyl)-N-(2-methoxyanilino)-1,3-thiazole-2-carboximidoyl cyanide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide

XLogP
4.55718
TPSA (Topological Polar Surface Area)
79.53
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
7
Heavy Atoms
27
Complexity
974.14685
Exact Mass
378.11505
Monoisotopic Mass
378.11505
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide

The XLogP value of 4.55718 indicates that (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.53 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide. Following Lipinski's Rule of Five, (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide?

The CAS number of (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide is 477188-75-3.

What is the molecular formula of (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide?

The molecular formula of (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide is C20H18N4O2S.

What is the molecular weight of (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide?

The molecular weight of (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide is 378.12 g/mol.

Where can I buy (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide?

You can request a quote for (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide?

Yes, KEHONG BIO provides custom synthesis services for (E)-4-(4-ethoxyphenyl)-N'-(2-methoxyphenyl)thiazole-2-carbohydrazonoyl cyanide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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