F0760-1813 structure

F0760-1813

TL;DR: F0760-1813 (CAS 477186-54-2) is a chemical compound with molecular formula C21H16F3N3S and molecular weight 399.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(E)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-3-[3-(trifluoromethyl)anilino]prop-2-enenitrile

Also Known As: F0760-1813, (E)-2-(4-(3,4-dimethylphenyl)thiazol-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)acrylonitrile, (2E)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile, (E)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-3-[3-(trifluoromethyl)anilino]prop-2-enenitrile

CAS: 477186-54-2
Molecular Formula C21H16F3N3S
Molecular Weight 399.10 g/mol
LogP 6.42232
Topological Polar Surface Area 48.71 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 399.1017
Heavy Atoms 28
Complexity 1074.9852

Chemical Identifiers

CAS Number 477186-54-2
SMILES CC1=C(C=C(C=C1)C2=CSC(=N2)/C(=C/NC3=CC=CC(=C3)C(F)(F)F)/C#N)C

Product Overview

F0760-1813 (CAS 477186-54-2), with molecular formula C21H16F3N3S and molecular weight 399.10 g/mol. IUPAC: (E)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-3-[3-(trifluoromethyl)anilino]prop-2-enenitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of F0760-1813

XLogP
6.42232
TPSA (Topological Polar Surface Area)
48.71
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
28
Complexity
1074.9852
Exact Mass
399.1017
Monoisotopic Mass
399.1017
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F0760-1813

The XLogP value of 6.42232 indicates that F0760-1813 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.71 Ų, F0760-1813 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0760-1813 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F0760-1813?

The CAS number of F0760-1813 is 477186-54-2.

What is the molecular formula of F0760-1813?

The molecular formula of F0760-1813 is C21H16F3N3S.

What is the molecular weight of F0760-1813?

The molecular weight of F0760-1813 is 399.10 g/mol.

Where can I buy F0760-1813?

You can request a quote for F0760-1813 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F0760-1813?

Yes, KEHONG BIO provides custom synthesis services for F0760-1813 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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