Colchicoside
TL;DR: Colchicoside (CAS 477-29-2) is a chemical compound with molecular formula C27H33NO11 and molecular weight 547.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(7S)-1,2,10-trimethoxy-9-oxo-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: Colchicoside, 3-Demethylcolchicine glucoside, Colchicine EP impurity D, Thiocolchicoside EP Impurity D, EC 207-513-0
| Molecular Formula | C27H33NO11 |
|---|---|
| Molecular Weight | 547.21 g/mol |
| LogP | -1.1 |
| Topological Polar Surface Area | 173.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 7 |
| Exact Mass | 547.2054 |
| Heavy Atoms | 39 |
| Complexity | 1010.0 |
Chemical Identifiers
| CAS Number | 477-29-2 |
|---|---|
| SMILES | CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O |
| InChIKey | UXAFRQPVHYZDED-ZZEDUEFDSA-N |
Product Overview
Colchicoside (CAS 477-29-2), with molecular formula C27H33NO11 and molecular weight 547.21 g/mol. IUPAC: N-[(7S)-1,2,10-trimethoxy-9-oxo-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of Colchicoside
Property Insights of Colchicoside
The XLogP value of -1.1 indicates that Colchicoside is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 173.0 Ų indicates high polarity, suggesting Colchicoside may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Colchicoside has 5 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchicoside?
The CAS number of Colchicoside is 477-29-2.
What is the molecular formula of Colchicoside?
The molecular formula of Colchicoside is C27H33NO11.
What is the molecular weight of Colchicoside?
The molecular weight of Colchicoside is 547.21 g/mol.
Where can I buy Colchicoside?
You can request a quote for Colchicoside directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchicoside?
Yes, KEHONG BIO provides custom synthesis services for Colchicoside and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.