F0737-0358
TL;DR: F0737-0358 (CAS 476643-11-5) is a chemical compound with molecular formula C15H9Cl2N3OS and molecular weight 348.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(2,5-dichlorothiophen-3-yl)-3-hydroxy-2-(1-methylbenzimidazol-2-yl)prop-2-enenitrile
Also Known As: F0737-0358, (E)-(2,5-dichloro-3-thenoyl)(1-methyl-1,3-dihydro-2H-1,3-benzimidazol-2-ylidene)acetonitrile, 3-(2,5-dichlorothiophen-3-yl)-2-[(2E)-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene]-3-oxopropanenitrile
| Molecular Formula | C15H9Cl2N3OS |
|---|---|
| Molecular Weight | 348.98 g/mol |
| LogP | 4.89148 |
| Topological Polar Surface Area | 61.84 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 348.98434 |
| Heavy Atoms | 22 |
| Complexity | 949.49774 |
Chemical Identifiers
| CAS Number | 476643-11-5 |
|---|---|
| SMILES | CN1C2=CC=CC=C2N=C1C(=C(C3=C(SC(=C3)Cl)Cl)O)C#N |
Product Overview
F0737-0358 (CAS 476643-11-5), with molecular formula C15H9Cl2N3OS and molecular weight 348.98 g/mol. IUPAC: 3-(2,5-dichlorothiophen-3-yl)-3-hydroxy-2-(1-methylbenzimidazol-2-yl)prop-2-enenitrile.
Chemical Property Profile of F0737-0358
Property Insights of F0737-0358
The XLogP value of 4.89148 indicates that F0737-0358 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.84 Ų falls within the moderate polarity range, balancing permeability and solubility for F0737-0358. Following Lipinski's Rule of Five, F0737-0358 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0737-0358?
The CAS number of F0737-0358 is 476643-11-5.
What is the molecular formula of F0737-0358?
The molecular formula of F0737-0358 is C15H9Cl2N3OS.
What is the molecular weight of F0737-0358?
The molecular weight of F0737-0358 is 348.98 g/mol.
Where can I buy F0737-0358?
You can request a quote for F0737-0358 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0737-0358?
Yes, KEHONG BIO provides custom synthesis services for F0737-0358 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.