RefChem:464188 structure

RefChem:464188

TL;DR: RefChem:464188 (CAS 476483-27-9) is a chemical compound with molecular formula C22H20N4O3S2 and molecular weight 452.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-amino-4-(5-methyl-2-methylsulfanylthiophen-3-yl)-1-(3-nitrophenyl)-5-oxo-4,6,7,8-tetrahydroquinoline-3-carbonitrile

Also Known As: 2-Amino-4-(5-methyl-2-(methylthio)thiophen-3-yl)-1-(3-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile, 2-amino-4-[5-methyl-2-(methylsulfanyl)-3-thienyl]-1-(3-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarbonitrile, 2-AMINO-4-(5-METHYL-2-(METHYLSULFANYL)-3-THIENYL)-1-(3-NITROPHENYL)-5-OXO-1,4,5,6,7,8-HEXAHYDRO-3-QUINOLINECARBONITRILE, 2-amino-4-(5-methyl-2-methylsulfanylthiophen-3-yl)-1-(3-nitrophenyl)-5-oxo-4,6,7,8-tetrahydroquinoline-3-carbonitrile, 2-AMINO-4-[5-METHYL-2-(METHYLSULFANYL)THIOPHEN-3-YL]-1-(3-NITROPHENYL)-5-OXO-1,4,5,6,7,8-HEXAHYDROQUINOLINE-3-CARBONITRILE

CAS: 476483-27-9
Molecular Formula C22H20N4O3S2
Molecular Weight 452.10 g/mol
LogP 4.9914
Topological Polar Surface Area 113.26 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 8
Rotatable Bonds 4
Exact Mass 452.0977
Heavy Atoms 31
Complexity 1205.5785

Chemical Identifiers

CAS Number 476483-27-9
SMILES CC1=CC(=C(S1)SC)C2C(=C(N(C3=C2C(=O)CCC3)C4=CC(=CC=C4)[N+](=O)[O-])N)C#N

Product Overview

RefChem:464188 (CAS 476483-27-9), with molecular formula C22H20N4O3S2 and molecular weight 452.10 g/mol. IUPAC: 2-amino-4-(5-methyl-2-methylsulfanylthiophen-3-yl)-1-(3-nitrophenyl)-5-oxo-4,6,7,8-tetrahydroquinoline-3-carbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RefChem:464188

XLogP
4.9914
TPSA (Topological Polar Surface Area)
113.26
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
8
Rotatable Bonds
4
Heavy Atoms
31
Complexity
1205.5785
Exact Mass
452.0977
Monoisotopic Mass
452.0977
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RefChem:464188

The XLogP value of 4.9914 indicates that RefChem:464188 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 113.26 Ų falls within the moderate polarity range, balancing permeability and solubility for RefChem:464188. Following Lipinski's Rule of Five, RefChem:464188 has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RefChem:464188?

The CAS number of RefChem:464188 is 476483-27-9.

What is the molecular formula of RefChem:464188?

The molecular formula of RefChem:464188 is C22H20N4O3S2.

What is the molecular weight of RefChem:464188?

The molecular weight of RefChem:464188 is 452.10 g/mol.

Where can I buy RefChem:464188?

You can request a quote for RefChem:464188 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RefChem:464188?

Yes, KEHONG BIO provides custom synthesis services for RefChem:464188 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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